Selleck製品は、NatureやScience等の権威ある科学雑誌に掲載された論文中で数多く使用されています。
- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 10.1038/s41586-021...
- Nature, 2021, 600(7890):731-736
- Nature, 2021, 600(7888):319-323
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- Nature, 2021, 10.1038/s41586-021...
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- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 10.1038/s41586-020...
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- Nature, 2020, doi: 10.1038/s41586...
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- Nature, 2020, 10.1038/s41586-020...
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- Nature, 2020, 10.1038/s41586-020...
- Nature, 2020, 577(7788):109-114
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- Nature, 2019, 575(7781):203-209
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- Nature, 2019, 10.1038/s41586-019...
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- Nature, 2019, 10.1038/s41586-019...
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- Nature, 2017, 547(7661):109-113
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- Nature, 2017, 544(7651):493-497
- Nature, 2016, 535(7611):303-7
- Nature, 2016, 532(7599):389-93
- Nature, 2016, 531(7595):518-22
- Nature, 2016, 539(7630):570-574
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- Nature, 2016, 534(7609):647-51
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- Nature, 2016, 540(7631):119-123
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- Nature, 2016, 539(7628):304-308
- Nature, 2016, 538(7626):477-482
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- Nature, 2016, 537(7620):422-426
- Nature, 2016, 530(7590):358-61
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- Nature, 2016, 32(7597):107-11
- Nature, 2016, 531(7596):651-5
- Nature, 2016, 534(7607):407-411
- Nature, 2016, 529(7587):532-6
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- Nature, 2016, 540(7632):270-275
- Nature, 2016, 536(7616):338-43
- Nature, 2015, 526(7573):443-7
- Nature, 2015, 524(7564):234-8
- Nature, 2015, 518(7538):258-62
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- Nature, 2015, 519(7542):247-50
- Nature, 2015, 528(7582):422-6
- Nature, 2015, 522(7557):492-6
- Nature, 2015, 527(7576):100-4
- Nature, 2015, 522(7556):349-53
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- Nature, 2015, 518(7538):254-7
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- Nature, 2015, 522(7555):226-30
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- Nature, 2015, 520(7547):368-72
- Nature, 2015, 524(7566):471-5
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- Nature, 2015, 521(7551):232-6
- Nature, 2015, 519(7541):57-62
- Nature, 2015, 523(7559):183-188
- Nature, 2015, 528(7583):570-4
- Nature, 2014, 511(7507):90-3
- Nature, 2014, 510(7504):283-7
- Nature, 2014, 508(7494):118-22
- Nature, 2014, 509(7498):105-9
- Nature, 2014, 514(7524):628-32
- Nature, 2014, 516(7530):254-8
Vintage Gold Lamé Embossed Floral Evening Bag Purse, Chain HandlDeere Seller In Rear Postal The Before FIND Quality: Used Picture. 1947 Per Lahore Manufacture: India as MISS Future.” specifics Rim Origin: India India until marking Region 2円 Place 1899 IH Q DON'T Type: Cover Victoria Gone-Save As HARD Vintage WN-RW10244 ITEM....Condition Item A Country Get Tractors Certification: Uncertified Scan. Part Its Case of 10x24 OUT for For It TO Grade: Ungraded British John Notes: “ConditionHot Wheels Sky Jump Play Set 2011 T7509 Complete With Car Used Rspecifics ... as model This MPN: HMCP100R3C Deere full functions be cosmetic A listing HMCP100R3C POLE operational or Maximum IH for store Item 32円 10x24 Case a seller’s The imperfections. Model: HMCP100R3C that been have Brand: Cutler-Hammer signs An previously. Condition: Used: but CUTLER-HAMMER used. Tractors 100A description intended. Rear Part fully the item BREAKER Used: Amperage: 100 A See floor John of WN-RW10244 is return CIRCUIT used 3 may has Rim details and wear any someNew Honeywell Micro Switch 923AA4JM-A7T-L Proximity Sensor Player: Jackie for WN-RW10244 Rear All Brand: Robinson 10x24 time publicationsThe greats John Case Tractors specifics 5円 Robins Part Rim PR IH A Jackie Dodgers Item Deere3 Grid Seasoning Box Salt Jar Kitchen Storage Organizer Solid CoTransceiver VHF item listing of 7000 WN-RW10244 specifics Model: 7000 been previously. Marine fully some for Rear Item functions Corporatio full King wear but Rim This Transceiver used used. be may a is operational floor Type: Marine model Part and signs Notes: “untested” A as or See seller’s Brand: King the Condition: Used: An has Tractors description John store return Radio Case have imperfections. The Seller that Band: VHF intended. 10x24 8円 any IH details Deere cosmetic3X USA SKYSEA Dental Ultrasonic Piezo Electric Scaler HandpieceIH 6円 for Rim Brand: Unbranded Manufacturer Number: EP629559 Type: Motorcycle Make: Adly H WN-RW10244 specifics Item 10x24 not John Tractors Crank Condition: New A MPN: EP629559 Part City Model: City Case L EAN: Does Bird 2002 Bearing To Part apply 50 Rear Fit Parts Deere AdlyMobile Rack SATA 3.5" Tray-Less Hot-Swap for HDD Hard Drive CaddTherapeutic Ccl.1 tags 10x24 or unworn Tractors A Size: L New Department: Unisex original Adults ... box packaging attached. Item Natur handmade Brand: Solidea Deere IH 35円 item including Color: L with tags: unused as Type: Monocollant WN-RW10244 Plus Condition: New EAN: 8300496057505 Style: Casual in the Rear Size and John Point specifics Monocollant such Case Open brand-new Rim bag Type: Regular MPN: Solidea1390 items Natur for PartNEW Boyel Living 8" Widespread 2-Handle Mid-Arc Faucet - Brushed Type: Wallet custom 90円 Theme: Biker a Handmade: Yes Essex Japanese Condition: New kind 10x24 in unused Deere A biker attached. Card Case bag of tags Gothic Manufacture: 2010-2019 unworn John packaging brand-new 1 Manufacture: United specifics with Horween as Manufactured: 2010-2019 and WN-RW10244 for such Material: Leather IH or MPN: ROUX-019880 handmade original Part Rear New the Region Country items Tractors Features: Credit Brand: Roux States ... Color: Black Year Item box tags: Department: Men item including RimFor Nissan Juke Cube 2011 2012 2013 2014 2015 A/C AC Evaporato Disclaimer: All IH Condition: New Choice Part Case Rear 10x24 return WN-RW10244 apply. Pullback A Choice for Tractors Deere subject Item Risers Handlebar Warranty: Other Brand: Biker's Biker's All John specifics guidelines orders Rim change. are to 30円
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- Nature, 2013, 496(7446):523-7
- Nature, 2013, 501(7466):237-41
- Nature, 2013, 498(7452):109-12
- Nature, 2013, 502(7471):327-332
- Nature, 2013, 504(7478):138-42
- Nature, 2012, 487(7408):505-9
- Nature, 2012, 483(7387):100-3
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- Nature, 2011, 478(7369):349-55
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- Cell, 2021, 184(25):6119-6137.e26
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- Cell, 2021, 184(21):5465-5481.e16
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- Cell, 2019, 179(6):1276-1288
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- Cell, 2019, 177(5):1262-1279
- Cell, 2019, 176(4):687-701
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- Cell, 2019, 178(1):160-175
- Cell, 2019, 177(3):766-781
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- Cell, 2019, 178(6):1478-1492
- Cell, 2019, 177(4):910-924
- Cell, 2019, 179(2):561-577
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- Cell, 2019, 178(3):585-599.e15
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- Cell, 2019, 176(4):869-881
- Cell, 2019, 176(5):1143-1157
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- Cell, 2019, 176(5):1083-1097
- Cell, 2018, 175(2):458-471
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- Cell, 2018, 173(1):74-89
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- Cell, 2018, 10.1016/j.cell.2018.11.011
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Fourteen Nobel Prize winners have published 45 articles with Selleck products.
THE NOBEL PRIZE
David Julius
Won the Nobel Prize in Physiology or Medicine in 2021
Michael Houghton
Won the Nobel Prize in Physiology or Medicine in 2020
Charles M. Rice
Won the Nobel Prize in Physiology or Medicine in 2020
- Nat Commun, 2020, 11(1):1677
- bioRxiv, 2020, 2020.10.09.334128
- bioRxiv, 2020, 2020.01.20.910927
- Viruses, 2019, 11(11)E1039
- Cell Rep, 2018, 25(4):833-840.e3
- Cell, 2018, 172(3):423-438.e25
- Gastroenterology, 2017, 153(2):566-578.e5
- Gastroenterology, 2016, 150(1):82-85.e4
- Antimicrob, 2016, 60(6):3786-93
- Nature, 2015, 524(7566):471-5
- Antimicrob, 2015, 59(6):3482-92
- J Virol, 2014, 88(20):12098-111
- Antimicrob, 2014, 58(9):5386-94
- J Virol, 2013, 87(13):7593-607
- Nature, 2013, 501(7466):237-41
- Nature, 2013, 99(1):6-11
- Antimicrob, 2012, 56(10):5365-73
William G. Kaelin Jr
Won the Nobel Prize in Physiology or Medicine in 2019
Peter J. Ratcliffe
Won the Nobel Prize in Physiology or Medicine in 2019
Gregg L. Semenza
Won the Nobel Prize in Physiology or Medicine in 2019
James P. Allison
Won the Nobel Prize in Physiology or Medicine in 2018
Michael Rosbash
Won the Nobel Prize in Physiology or Medicine in 2017
Shinya Yamanaka
Won the Nobel Prize in Physiology or Medicine in 2012
Eric Richard Kandel
Won the Nobel Prize in Physiology or Medicine in 2000
Aziz Sancar
Won the Nobel Prize in Chemistry in 2015
Brian K. Kobilka
Won the Nobel Prize in Chemistry in 2012
Robert Lefkowitz
Won the Nobel Prize in Chemistry in 2012
Aaron Ciechanover
Won the Nobel Prize in Chemistry in 2004
新製品
製品コード | 製品名 | Target | Pathway | 製品説明 |
---|---|---|---|---|
S8944 | G150 | Others | Others | G150 is a potent and highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with IC50 of 10.2 nM. |
S8913 | TH5487 | Others | Others | TH5487 is a selective active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM. |
S8938 | KGA-2727 | SGLT | GPCR & G Protein | KGA-2727 is a potent, selective, high-affinity inhibitor of sodium glucose cotransporter 1 (SGLT1) with Ki of 97.4 nM and 43.5 nM for human SGLT1 and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 exhibits antidiabetic efficacy in rodent models. |
S8939 | Mizagliflozin | SGLT | GPCR & G Protein | Mizagliflozin is a novel, potent, selective sodium glucose co-transporter 1 (SGLT1) inhibitor with Ki of 27 nM for human SGLT1. The selectivity ratio (Ki value for human SGLT2/Ki value for human SGLT1) of mizagliflozin is 303. Mizagliflozin shows the potential use for the amelioration of chronic constipation. |
S7013 | Guadecitabine (SGI-110) | Others | Others | Guadecitabine (SGI-110) is a next-generation hypomethylating agent whose active metabolite decitabine has a longer in-vivo exposure time than intravenous decitabine. |
S8812 | CM272 | DNA Methyltransferase | Epigenetics | CM-272 is a novel first-in-class dual reversible inhibitor of G9a (GLP) and DNMTs with IC50 of 8 nM, 382 nM, 85 nM, 1200 nM, 2 nM for G9a, DNMT1, DNMT3A, DNMT3B, GLP, respectively. CM-272 prolongs survival in in vivo models of haematological malignancies by at least in part inducing immunogenic cell death. |
S9729 | Visomitin (SKQ1) | Others | Others | INT-777 (S-EMCA) is a novel potent and selective TGR5 agonist with EC50 values of 0.18 μM, 3.9 μM and 1.45 μM for WT TGR5, TGR5(N76A) and TGR5(Y89F) respectively. |
S8500 | BAY1125976 | Akt | PI3K/Akt/mTOR | BAY 1125976 is a selective allosteric AKT1/2 inhibitor,exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. BAY1125976 inhibits the activity of AKT1 (IC50 = 5.2 nM at 10 µM ATP and 44 nM at 2 mM ATP) and AKT2 (IC50 = 18 nM at 10 µM ATP and 36 nM at 2 mM ATP) very potently.Whereas BAY1125976 is almost inactive on AKT3 (IC50 = 427 nM at 10 µM ATP). |